Hikaru Kodama, a degraded nurse, falls into a deviant trap and becomes a sex slave. In a secret area of the hospital she undergoes an erotic experiment. Hikaru shows the true nature of her ferocity. She proceeds to go on a splurge of sexually infused romps that turn her submissive, docile demeanor into a one-woman sex machine!

Hikaru Kodama can't seem to keep herself out of trouble. Or maybe, she gets her thrills by getting into trouble. Her plunge into a world of sexual obedience has taken an unexpected turn as she unwittingly agrees to become the new wife of the sadistic Dr. Hirasaka. Despite Dr. Hirasaka's emotional plea for marriage, he cannot hide his true desire to keep experimenting on his luscious bride to be. In a twist of fate Ai asks to be "made into a woman" A temptation the doctor can not resist to join in on. This 3 way action will make you twiddle in the middle. A match of raw, diabolical sex games that will ignite the fantasies of perverts the world over. Night Shift Nurses 2 is the shocking continuation of this mind blowing, chaotic series that will have you screaming, "My ass is not a blender"!

Hikaru has dived into a life of hedonistic sex games which have culminated in the day every girl dreams of: her wedding day. Now the blushing bride and her perverted doctor husband look forward to slower-paced days. But that doesn't last for long. In no time these perverts are back to their old ways, including sexual fetishes that give the term "honeymoon" a new demented meaning. A new town leaves all kinds of new places to experiment...